Medical management of chronic myelogenous leukemia

This valuable reference provides a timely summary of current therapies for chronic myelogenous leukemia (CML), discussing both basic pathophysiology and new experimental strategies. Combining the insights of over 30 prominent researchers in the field, Medical Management of Chronic Myelogenous Leukemia ·compares interferon therapy with conventional chemotherapy ·covers chronic, accelerated, and Philadelphia-negative phases ·details standard therapy with IFN- regimens and allogenic stem cell transplantation ·describes the utility and limitations of CML animal models ·profiles clinical trials testing IFN in combination with other agents ·assesses improvements in survival times among CML patients ·reviews the effectiveness of Southern blot monitoring ·traces the development of oligonucleotides as potential therapeutic agents ·outlines therapy with monoclonal antibodies, targeted NK cells, and immune T cells ·and more! Containing over 1500 references, tables, drawings, and photographs, Medical Management of Chronic Myelogenous Leukemia is suitable for clinical oncologists, hematologists, immunologists and researchers in the fields of tumor immunology and cancer immunotherapy, internists, and residents, fellows, and medical school students in these disciplines.